274202

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3664508..3665105 Replicon chromosome
Accession NZ_CP119566
Organism Pararhizobium sp. T808

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag PYR65_RS17985 Protein ID WP_276118964.1
Coordinates 3664824..3665105 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PYR65_RS17980 Protein ID WP_276118963.1
Coordinates 3664508..3664807 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYR65_RS17960 3660401..3660928 + 528 WP_276118960.1 plant virulence effector HPE1-like domain-containing protein -
PYR65_RS17965 3661149..3661637 - 489 WP_276118961.1 DUF523 domain-containing protein -
PYR65_RS17970 3661700..3662014 - 315 WP_060636467.1 hypothetical protein -
PYR65_RS17975 3662059..3664413 - 2355 WP_276118962.1 glycine--tRNA ligase subunit beta -
PYR65_RS17980 3664508..3664807 - 300 WP_276118963.1 HigA family addiction module antitoxin Antitoxin
PYR65_RS17985 3664824..3665105 - 282 WP_276118964.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PYR65_RS17990 3665201..3667144 - 1944 WP_276118965.1 DUF2207 domain-containing protein -
PYR65_RS17995 3667190..3668458 - 1269 WP_276118966.1 3-phosphoshikimate 1-carboxyvinyltransferase -
PYR65_RS18000 3668559..3669107 - 549 WP_276118967.1 LemA family protein -
PYR65_RS18005 3669314..3669511 + 198 WP_276118968.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(5-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(7-93)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10403.89 Da        Isoelectric Point: 9.1862

>T274202 WP_276118964.1 NZ_CP119566:c3665105-3664824 [Pararhizobium sp. T808]
VIRSFKGKISAALADGSMKKGFPTDLVRRAQQLLVLLNAACDVKDLRSPPGNRLEKLSGDREGQYSIRINQQWRICFVWS
NGGADDVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11130.86 Da        Isoelectric Point: 5.8701

>AT274202 WP_276118963.1 NZ_CP119566:c3664807-3664508 [Pararhizobium sp. T808]
MNDIGLPAIHPGEILKDLYLEPLDISAGTLAKKLNVPRTRIERIVTGKTGVTSDTALRLARFFDTTPELWMNLQVSYDLT
IEAERKRAEIERIPVRDAA

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References