Detailed information of TA system TA274157

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 3072606..3073002
• Replicon: chromosome
• Accession: NZ_CP119528
• Organism: Enterococcus faecalis strain 3143

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: Q82Z30
• Locus tag: P0083_RS15330
• Protein ID: WP_002387585.1
• Coordinates: 3072859..3073002 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	3072606..3072748 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P0083_RS15320	3068211..3068315	+	105	WP_021164545.1	putative holin-like toxin	-
P0083_RS15325	3068505..3072263	-	3759	WP_010706868.1	WxL domain-containing protein	-
-	3072606..3072748	-	143	-	-	Antitoxin
P0083_RS15330	3072859..3073002	+	144	WP_002387585.1	putative holin-like toxin	Toxin
P0083_RS15335	3073192..3076251	-	3060	WP_002387586.1	WxL domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5244.37 Da
• Isoelectric Point: 10.5719

>T274157 WP_002387585.1 NZ_CP119528:3072859-3073002 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILKVVKEDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 143 bp

>AT274157 NZ_CP119528:c3072748-3072606 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCTTT
TTAGTTACAAAAAATAACCGTACTCAGTCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAA

Structures

Toxin

• AlphaFold DB: A0A059MXV6

Antitoxin