Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) txpA-ratA/-
Location 3067917..3068315 Replicon chromosome
Accession NZ_CP119528
Organism Enterococcus faecalis strain 3143

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag P0083_RS15320 Protein ID WP_021164545.1
Coordinates 3068211..3068315 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 3067917..3068071 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0083_RS15305 3063595..3064227 - 633 WP_002358972.1 RloB family protein -
P0083_RS15310 3064236..3065531 - 1296 WP_002379013.1 ATP-binding protein -
P0083_RS15315 3065993..3067609 + 1617 WP_002379014.1 phosphatase PAP2/LCP family protein -
- 3067917..3068071 - 155 - - Antitoxin
P0083_RS15320 3068211..3068315 + 105 WP_021164545.1 putative holin-like toxin Toxin
P0083_RS15325 3068505..3072263 - 3759 WP_010706868.1 WxL domain-containing protein -
P0083_RS15330 3072859..3073002 + 144 WP_002387585.1 putative holin-like toxin -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-34)


Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3813.70 Da        Isoelectric Point: 10.3686

>T274153 WP_021164545.1 NZ_CP119528:3068211-3068315 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 105 bp


Antitoxin


Download         Length: 155 bp

>AT274153 NZ_CP119528:c3068071-3067917 [Enterococcus faecalis]
TTTTTAGGTAAGTGTGCTATAATAGCAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCGGTTTAAGA
CGGTGACCTTTTGGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References