Detailed information of TA system TA274149

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-RNAII/-
• Location: 2896171..2896430
• Replicon: chromosome
• Accession: NZ_CP119528
• Organism: Enterococcus faecalis strain 3143

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: P0083_RS14505
• Protein ID: WP_021164442.1
• Coordinates: 2896329..2896430 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	2896171..2896375 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P0083_RS14475	2891423..2892376	-	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-
P0083_RS14480	2892415..2893170	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
P0083_RS14485	2893167..2894132	-	966	WP_002387376.1	iron chelate uptake ABC transporter family permease subunit	-
P0083_RS14490	2894129..2895076	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
P0083_RS14495	2895261..2895713	+	453	WP_002378959.1	YueI family protein	-
P0083_RS14500	2895895..2895996	-	102	WP_021164441.1	putative holin-like toxin	-
-	2896171..2896375	+	205	-	-	Antitoxin
P0083_RS14505	2896329..2896430	-	102	WP_021164442.1	putative holin-like toxin	Toxin
P0083_RS14510	2896621..2898891	-	2271	WP_002399785.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
P0083_RS14515	2899062..2899562	+	501	WP_002378961.1	cysteine hydrolase family protein	-
P0083_RS14520	2900123..2901019	+	897	WP_002354953.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3625.38 Da
• Isoelectric Point: 4.5869

>T274149 WP_021164442.1 NZ_CP119528:c2896430-2896329 [Enterococcus faecalis]
MSIEATLELMISFATLVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 205 bp

>AT274149 NZ_CP119528:2896171-2896375 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTA

Structures

Antitoxin