Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 2713724..2714332 Replicon chromosome
Accession NZ_CP119392
Organism Rhodanobacter sp. AS-Z3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PY254_RS12035 Protein ID WP_281012284.1
Coordinates 2714081..2714332 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PY254_RS12030 Protein ID WP_281012283.1
Coordinates 2713724..2714014 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PY254_RS12005 (PY254_12005) 2708771..2709499 - 729 WP_281012278.1 hypothetical protein -
PY254_RS12010 (PY254_12010) 2709867..2711132 + 1266 WP_281012279.1 phospholipase D-like domain-containing protein -
PY254_RS12015 (PY254_12015) 2711236..2711697 - 462 WP_281012280.1 isoprenylcysteine carboxylmethyltransferase family protein -
PY254_RS12020 (PY254_12020) 2712296..2712568 - 273 WP_281012281.1 hypothetical protein -
PY254_RS12025 (PY254_12025) 2713227..2713520 - 294 WP_281012282.1 hypothetical protein -
PY254_RS12030 (PY254_12030) 2713724..2714014 - 291 WP_281012283.1 helix-turn-helix domain-containing protein Antitoxin
PY254_RS12035 (PY254_12035) 2714081..2714332 - 252 WP_281012284.1 hypothetical protein Toxin
PY254_RS12040 (PY254_12040) 2714436..2715638 - 1203 WP_281012285.1 trans-2-enoyl-CoA reductase family protein -
PY254_RS12045 (PY254_12045) 2715774..2716781 + 1008 WP_281012286.1 ligase-associated DNA damage response exonuclease -
PY254_RS12050 (PY254_12050) 2716781..2718376 + 1596 WP_281012287.1 ATP-dependent DNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(40-73)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9299.68 Da        Isoelectric Point: 10.6204

>T274050 WP_281012284.1 NZ_CP119392:c2714332-2714081 [Rhodanobacter sp. AS-Z3]
MIFVETPLFTRQIKLLLSDDDYGTFQRTLADNPQAGDVIPGTGGLRKVRVAAKGHGKSGGARVIYYHFNFRLTHRPVVRL
SQE

Download         Length: 252 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10602.04 Da        Isoelectric Point: 8.8746

>AT274050 WP_281012283.1 NZ_CP119392:c2714014-2713724 [Rhodanobacter sp. AS-Z3]
VDAKQFASFFESVTQMDEIVHGVREPSREFHIDAIGVTDIRKATGLSQARFATLIDVQVGTLRNWEQGRREPTGPAKALL
RAISRDPKNVLQALAG

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References