Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2485424..2485608 Replicon chromosome
Accession NZ_CP119344
Organism Staphylococcus aureus strain N29CSA11

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag P1A16_RS12385 Protein ID WP_000482647.1
Coordinates 2485501..2485608 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2485424..2485484 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1A16_RS12370 (P1A16_12370) 2480954..2481121 - 168 WP_001790576.1 hypothetical protein -
P1A16_RS12375 (P1A16_12375) 2481352..2483085 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
P1A16_RS12380 (P1A16_12380) 2483110..2484873 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2485424..2485484 + 61 - - Antitoxin
P1A16_RS12385 (P1A16_12385) 2485501..2485608 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
P1A16_RS12390 (P1A16_12390) 2485742..2486128 - 387 WP_000779360.1 flippase GtxA -
P1A16_RS12395 (P1A16_12395) 2486386..2487528 + 1143 WP_001176863.1 glycerate kinase -
P1A16_RS12400 (P1A16_12400) 2487588..2488247 + 660 WP_000831298.1 membrane protein -
P1A16_RS12405 (P1A16_12405) 2488429..2489640 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
P1A16_RS12410 (P1A16_12410) 2489763..2490236 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T274020 WP_000482647.1 NZ_CP119344:c2485608-2485501 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT274020 NZ_CP119344:2485424-2485484 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References