Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2203291..2203488 Replicon chromosome
Accession NZ_CP119344
Organism Staphylococcus aureus strain N29CSA11

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag P1A16_RS10905 Protein ID WP_001802298.1
Coordinates 2203384..2203488 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2203291..2203329 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1A16_RS10880 (P1A16_10880) 2199466..2200131 - 666 WP_001024095.1 SDR family oxidoreductase -
P1A16_RS10885 (P1A16_10885) 2200283..2200603 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
P1A16_RS10890 (P1A16_10890) 2200605..2201585 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
P1A16_RS10895 (P1A16_10895) 2201851..2202942 + 1092 WP_000495681.1 hypothetical protein -
P1A16_RS10900 (P1A16_10900) 2203271..2203345 + 75 Protein_2107 hypothetical protein -
- 2203291..2203329 + 39 - - Antitoxin
P1A16_RS10905 (P1A16_10905) 2203384..2203488 - 105 WP_001802298.1 hypothetical protein Toxin
P1A16_RS10910 (P1A16_10910) 2204168..2204326 + 159 WP_001792784.1 hypothetical protein -
P1A16_RS10915 (P1A16_10915) 2204984..2205841 - 858 WP_000370930.1 HAD family hydrolase -
P1A16_RS10920 (P1A16_10920) 2205909..2206691 - 783 WP_031590911.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T274018 WP_001802298.1 NZ_CP119344:c2203488-2203384 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT274018 NZ_CP119344:2203291-2203329 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References