Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 2260363..2260560 Replicon chromosome
Accession NZ_CP119341
Organism Staphylococcus aureus strain N29CSA02

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag P1A17_RS11310 Protein ID WP_001802298.1
Coordinates 2260456..2260560 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2260363..2260401 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1A17_RS11285 2256538..2257203 - 666 WP_001024095.1 SDR family oxidoreductase -
P1A17_RS11290 2257355..2257675 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
P1A17_RS11295 2257677..2258657 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
P1A17_RS11300 2258923..2260014 + 1092 WP_000495681.1 hypothetical protein -
P1A17_RS11305 2260343..2260417 + 75 Protein_2188 hypothetical protein -
- 2260363..2260401 + 39 - - Antitoxin
P1A17_RS11310 2260456..2260560 - 105 WP_001802298.1 hypothetical protein Toxin
P1A17_RS11315 2261240..2261398 + 159 WP_001792784.1 hypothetical protein -
P1A17_RS11320 2262056..2262913 - 858 WP_000370930.1 HAD family hydrolase -
P1A17_RS11325 2262981..2263763 - 783 WP_031590911.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T274009 WP_001802298.1 NZ_CP119341:c2260560-2260456 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT274009 NZ_CP119341:2260363-2260401 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References