Detailed information of TA system TA273999

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1920247..1920427
• Replicon: chromosome
• Accession: NZ_CP119341
• Organism: Staphylococcus aureus strain N29CSA02

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: P1A17_RS09315
• Protein ID: WP_001801861.1
• Coordinates: 1920247..1920342 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1920370..1920427 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P1A17_RS09290	1916302..1916928	+	627	WP_000669028.1	hypothetical protein	-
P1A17_RS09295	1917015..1917698	+	684	WP_000957233.1	exotoxin beta-grasp domain-containing protein	-
P1A17_RS09300	1917725..1918477	+	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
P1A17_RS09305	1918609..1919235	-	627	Protein_1831	ImmA/IrrE family metallo-endopeptidase	-
P1A17_RS09310	1919349..1919795	-	447	WP_000747805.1	DUF1433 domain-containing protein	-
P1A17_RS09315	1920247..1920342	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1920370..1920427	-	58	-	-	Antitoxin
P1A17_RS09320	1920465..1920563	+	99	Protein_1834	hypothetical protein	-
P1A17_RS09325	1920993..1922117	-	1125	WP_223876714.1	hypothetical protein	-
P1A17_RS09330	1922179..1922688	-	510	WP_224684909.1	hypothetical protein	-
P1A17_RS09335	1922948..1924120	+	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
P1A17_RS09340	1924091..1924852	-	762	WP_224684922.1	DNA adenine methylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	1913743..1944375	30632
	-	flank	IS/Tn	-	-	1922948..1924120	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T273999 WP_001801861.1 NZ_CP119341:1920247-1920342 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT273999 NZ_CP119341:c1920427-1920370 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin