Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2515479..2515663 Replicon chromosome
Accession NZ_CP119340
Organism Staphylococcus aureus strain N28CSA05

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag P1A15_RS12545 Protein ID WP_000482647.1
Coordinates 2515556..2515663 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2515479..2515539 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1A15_RS12530 (P1A15_12530) 2511009..2511176 - 168 WP_001790576.1 hypothetical protein -
P1A15_RS12535 (P1A15_12535) 2511407..2513140 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
P1A15_RS12540 (P1A15_12540) 2513165..2514928 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2515479..2515539 + 61 - - Antitoxin
P1A15_RS12545 (P1A15_12545) 2515556..2515663 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
P1A15_RS12550 (P1A15_12550) 2515797..2516183 - 387 WP_000779360.1 flippase GtxA -
P1A15_RS12555 (P1A15_12555) 2516441..2517583 + 1143 WP_001176863.1 glycerate kinase -
P1A15_RS12560 (P1A15_12560) 2517643..2518302 + 660 WP_000831298.1 membrane protein -
P1A15_RS12565 (P1A15_12565) 2518484..2519695 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
P1A15_RS12570 (P1A15_12570) 2519818..2520291 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T273996 WP_000482647.1 NZ_CP119340:c2515663-2515556 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT273996 NZ_CP119340:2515479-2515539 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References