Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2232021..2232218 Replicon chromosome
Accession NZ_CP119340
Organism Staphylococcus aureus strain N28CSA05

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag P1A15_RS11055 Protein ID WP_001802298.1
Coordinates 2232114..2232218 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2232021..2232059 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1A15_RS11030 (P1A15_11030) 2228196..2228861 - 666 WP_001024095.1 SDR family oxidoreductase -
P1A15_RS11035 (P1A15_11035) 2229013..2229333 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
P1A15_RS11040 (P1A15_11040) 2229335..2230315 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
P1A15_RS11045 (P1A15_11045) 2230581..2231672 + 1092 WP_000495681.1 hypothetical protein -
P1A15_RS11050 (P1A15_11050) 2232001..2232075 + 75 Protein_2137 hypothetical protein -
- 2232021..2232059 + 39 - - Antitoxin
P1A15_RS11055 (P1A15_11055) 2232114..2232218 - 105 WP_001802298.1 hypothetical protein Toxin
P1A15_RS11060 (P1A15_11060) 2232898..2233056 + 159 WP_001792784.1 hypothetical protein -
P1A15_RS11065 (P1A15_11065) 2233714..2234571 - 858 WP_000370930.1 HAD family hydrolase -
P1A15_RS11070 (P1A15_11070) 2234639..2235421 - 783 WP_031590911.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T273994 WP_001802298.1 NZ_CP119340:c2232218-2232114 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT273994 NZ_CP119340:2232021-2232059 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References