Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2227575..2227772 Replicon chromosome
Accession NZ_CP119338
Organism Staphylococcus aureus strain N09HSA11

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag P1A14_RS11030 Protein ID WP_001802298.1
Coordinates 2227668..2227772 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2227575..2227613 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1A14_RS11005 (P1A14_11005) 2223750..2224415 - 666 WP_001024095.1 SDR family oxidoreductase -
P1A14_RS11010 (P1A14_11010) 2224567..2224887 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
P1A14_RS11015 (P1A14_11015) 2224889..2225869 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
P1A14_RS11020 (P1A14_11020) 2226135..2227226 + 1092 WP_000495681.1 hypothetical protein -
P1A14_RS11025 (P1A14_11025) 2227555..2227629 + 75 Protein_2135 hypothetical protein -
- 2227575..2227613 + 39 - - Antitoxin
P1A14_RS11030 (P1A14_11030) 2227668..2227772 - 105 WP_001802298.1 hypothetical protein Toxin
P1A14_RS11035 (P1A14_11035) 2228289..2228459 + 171 WP_001792292.1 transposase -
P1A14_RS11040 (P1A14_11040) 2228452..2228610 + 159 WP_001792784.1 hypothetical protein -
P1A14_RS11045 (P1A14_11045) 2229268..2230125 - 858 WP_000370930.1 HAD family hydrolase -
P1A14_RS11050 (P1A14_11050) 2230193..2230975 - 783 WP_031590911.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T273985 WP_001802298.1 NZ_CP119338:c2227772-2227668 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 39 bp

>AT273985 NZ_CP119338:2227575-2227613 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References