Detailed information of TA system TA273866

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 45036..45241
• Replicon: plasmid pCFSAN126951_03
• Accession: NZ_CP119162
• Organism: Enterococcus faecalis strain GENOMIC22-006

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: P0D81_RS16950
• Protein ID: WP_002387930.1
• Coordinates: 45140..45241 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	45036..45100 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P0D81_RS16915	40371..40679	-	309	Protein_48	ATP-binding cassette domain-containing protein	-
P0D81_RS16920	40820..41500	-	681	WP_002319817.1	IS6-like element ISS1N family transposase	-
P0D81_RS16925	41537..41815	-	279	WP_010778048.1	hypothetical protein	-
P0D81_RS16930	41946..42959	-	1014	WP_002396062.1	replication initiator protein A	-
P0D81_RS16935	43218..43574	-	357	WP_002360663.1	hypothetical protein	-
P0D81_RS16940	43567..44349	-	783	WP_002369746.1	ParA family protein	-
P0D81_RS16945	44603..44899	-	297	WP_010717413.1	hypothetical protein	-
-	45036..45100	+	65	-	-	Antitoxin
P0D81_RS16950	45140..45241	-	102	WP_002387930.1	type I toxin-antitoxin system Fst family toxin	Toxin
P0D81_RS16955	45332..45547	-	216	WP_275527567.1	excinuclease ABC subunit C	-
P0D81_RS16960	45504..45854	-	351	WP_002395322.1	hypothetical protein	-
P0D81_RS16965	45851..47020	-	1170	WP_275527574.1	Y-family DNA polymerase	-
P0D81_RS16970	47036..47641	-	606	WP_000238804.1	recombinase family protein	-
P0D81_RS16975	47772..48587	+	816	WP_275527568.1	DUF4158 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	erm(B)	-	1..70159	70159

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3731.42 Da
• Isoelectric Point: 4.1672

>T273866 WP_002387930.1 NZ_CP119162:c45241-45140 [Enterococcus faecalis]
VKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT273866 NZ_CP119162:45036-45100 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin