Detailed information of TA system TA273862

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 3041904..3042098
• Replicon: chromosome
• Accession: NZ_CP119159
• Organism: Enterococcus faecalis strain GENOMIC22-006

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: P0D81_RS15105
• Protein ID: WP_015543884.1
• Coordinates: 3041904..3041999 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	3042034..3042098 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
P0D81_RS15085	3037083..3038198	+	1116	WP_002379062.1	FAD-dependent oxidoreductase	-
P0D81_RS15090	3038265..3039419	-	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
P0D81_RS15095	3039434..3039871	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
P0D81_RS15100	3039886..3041658	-	1773	WP_010706745.1	PTS mannitol-specific transporter subunit IIBC	-
P0D81_RS15105	3041904..3041999	+	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	3042034..3042098	-	65	-	-	Antitoxin
P0D81_RS15110	3042254..3042688	-	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
P0D81_RS15115	3042699..3044732	-	2034	WP_002387671.1	PRD domain-containing protein	-
P0D81_RS15120	3044723..3046465	-	1743	WP_002399652.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T273862 WP_015543884.1 NZ_CP119159:3041904-3041999 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT273862 NZ_CP119159:c3042098-3042034 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin