273860

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2750691..2750923 Replicon chromosome
Accession NZ_CP119159
Organism Enterococcus faecalis strain GENOMIC22-006

Toxin (Protein)


Gene name txpA Uniprot ID Q837V5
Locus tag P0D81_RS13680 Protein ID WP_002366178.1
Coordinates 2750807..2750923 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2750691..2750896 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D81_RS13660 2746178..2747266 - 1089 WP_002355572.1 diacylglycerol kinase -
P0D81_RS13665 2747285..2748715 - 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
P0D81_RS13670 2748715..2750184 - 1470 WP_002361259.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
P0D81_RS13675 2750184..2750489 - 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
- 2750691..2750896 + 206 - - Antitoxin
P0D81_RS13680 2750807..2750923 - 117 WP_002366178.1 putative holin-like toxin Toxin
P0D81_RS13685 2751071..2753101 - 2031 WP_002361258.1 NAD-dependent DNA ligase LigA -
P0D81_RS13690 2753227..2755485 - 2259 WP_002363179.1 DNA helicase PcrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4108.01 Da        Isoelectric Point: 5.9482

>T273860 WP_002366178.1 NZ_CP119159:c2750923-2750807 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFVILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT273860 NZ_CP119159:2750691-2750896 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAA
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1G1S9M0

Antitoxin

Download structure file

References