273851

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 320334..320766 Replicon chromosome
Accession NZ_CP119159
Organism Enterococcus faecalis strain GENOMIC22-006

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag P0D81_RS01630 Protein ID WP_021164545.1
Coordinates 320334..320438 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 320590..320766 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0D81_RS01620 315647..315790 - 144 WP_002387585.1 putative holin-like toxin -
P0D81_RS01625 316386..320144 + 3759 WP_010706868.1 WxL domain-containing protein -
P0D81_RS01630 320334..320438 - 105 WP_021164545.1 putative holin-like toxin Toxin
- 320590..320766 + 177 - - Antitoxin
P0D81_RS01635 321040..322656 - 1617 WP_002379014.1 phosphatase PAP2/LCP family protein -
P0D81_RS01640 323118..324413 + 1296 WP_002379013.1 ATP-binding protein -
P0D81_RS01645 324422..325054 + 633 WP_002358972.1 RloB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-34)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3813.70 Da        Isoelectric Point: 10.3686

>T273851 WP_021164545.1 NZ_CP119159:c320438-320334 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 105 bp

Antitoxin


Download         Length: 177 bp

>AT273851 NZ_CP119159:320590-320766 [Enterococcus faecalis]
TGTGCTATAATAGCAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCGGTTTAAGACGGTGACCTTTT
GGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAACAGCTTTTAGGATTCCG
AAGATTAACGTTGCGAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References