Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 660334..660851 Replicon chromosome
Accession NZ_CP119127
Organism Sphingobium sp. WTD-1

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag N6H05_RS03405 Protein ID WP_188084047.1
Coordinates 660585..660851 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N6H05_RS03400 Protein ID WP_284112714.1
Coordinates 660334..660588 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6H05_RS03375 (N6H05_03375) 657432..657752 + 321 WP_284112711.1 hypothetical protein -
N6H05_RS03380 (N6H05_03380) 657778..658320 - 543 WP_284112712.1 hypothetical protein -
N6H05_RS03385 (N6H05_03385) 658466..658909 + 444 WP_017500007.1 hypothetical protein -
N6H05_RS03390 (N6H05_03390) 659052..659711 + 660 WP_010335474.1 hypothetical protein -
N6H05_RS03395 (N6H05_03395) 659921..660217 - 297 WP_284112713.1 LysR family transcriptional regulator -
N6H05_RS03400 (N6H05_03400) 660334..660588 + 255 WP_284112714.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N6H05_RS03405 (N6H05_03405) 660585..660851 + 267 WP_188084047.1 Txe/YoeB family addiction module toxin Toxin
N6H05_RS03410 (N6H05_03410) 660893..661420 - 528 WP_284112715.1 DUF2199 domain-containing protein -
N6H05_RS03415 (N6H05_03415) 661512..663407 - 1896 WP_284112716.1 phosphomethylpyrimidine synthase ThiC -
N6H05_RS03420 (N6H05_03420) 663680..663964 + 285 WP_284112717.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10130.51 Da        Isoelectric Point: 9.6015

>T273806 WP_188084047.1 NZ_CP119127:660585-660851 [Sphingobium sp. WTD-1]
VKIVFGGQAWRDYVAWAADDPKVLARINALIEECRRDPFRGTGKPEPLRQNLAGWWSRRITGEHRLVYRVSGSGDTQALE
VLSCRYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9131.45 Da        Isoelectric Point: 5.0499

>AT273806 WP_284112714.1 NZ_CP119127:660334-660588 [Sphingobium sp. WTD-1]
MQTVSVSETRANLKAVLDRVVADKAPIQIVRPKGEGVVMISQSEWEGMQETLHLLASPANAHHLLEGIRQLDAGLGEEHE
LIAP

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References