Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2599336..2599520 Replicon chromosome
Accession NZ_CP119113
Organism Staphylococcus aureus strain GENOMIC22-002

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag PXV46_RS13095 Protein ID WP_000482647.1
Coordinates 2599413..2599520 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2599336..2599396 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXV46_RS13080 (PXV46_13080) 2594791..2594958 - 168 WP_001798790.1 hypothetical protein -
PXV46_RS13085 (PXV46_13085) 2595189..2596922 - 1734 WP_000486511.1 ABC transporter ATP-binding protein -
PXV46_RS13090 (PXV46_13090) 2596947..2598710 - 1764 WP_001064818.1 ABC transporter ATP-binding protein -
- 2599336..2599396 + 61 - - Antitoxin
PXV46_RS13095 (PXV46_13095) 2599413..2599520 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
PXV46_RS13100 (PXV46_13100) 2599654..2600040 - 387 WP_000779355.1 flippase GtxA -
PXV46_RS13105 (PXV46_13105) 2600307..2601449 + 1143 WP_001176859.1 glycerate kinase -
PXV46_RS13110 (PXV46_13110) 2601509..2602168 + 660 WP_000831300.1 hypothetical protein -
PXV46_RS13115 (PXV46_13115) 2602356..2603567 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
PXV46_RS13120 (PXV46_13120) 2603690..2604163 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T273779 WP_000482647.1 NZ_CP119113:c2599520-2599413 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT273779 NZ_CP119113:2599336-2599396 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References