Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 708413..708676 Replicon chromosome
Accession NZ_CP119109
Organism Staphylococcus aureus strain GENOMIC22-001

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag PXV45_RS03505 Protein ID WP_001802298.1
Coordinates 708413..708517 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 708512..708676 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXV45_RS03480 704312..704920 + 609 WP_000101714.1 TIR domain-containing protein -
PXV45_RS03485 705210..705992 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
PXV45_RS03490 706060..706917 + 858 WP_000370942.1 HAD family hydrolase -
PXV45_RS03495 707047..707139 - 93 WP_000220902.1 hypothetical protein -
PXV45_RS03500 707575..707733 - 159 WP_001792784.1 hypothetical protein -
PXV45_RS03505 708413..708517 + 105 WP_001802298.1 hypothetical protein Toxin
- 708512..708676 - 165 - - Antitoxin
PXV45_RS03515 709015..710106 - 1092 WP_000495673.1 hypothetical protein -
PXV45_RS03520 710372..711352 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
PXV45_RS03525 711354..711674 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PXV45_RS03530 711826..712491 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T273755 WP_001802298.1 NZ_CP119109:708413-708517 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT273755 NZ_CP119109:c708676-708512 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References