Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 411628..411812 Replicon chromosome
Accession NZ_CP119109
Organism Staphylococcus aureus strain GENOMIC22-001

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag PXV45_RS01950 Protein ID WP_000482647.1
Coordinates 411628..411735 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 411752..411812 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PXV45_RS01925 406985..407458 + 474 WP_000456489.1 GyrI-like domain-containing protein -
PXV45_RS01930 407581..408792 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
PXV45_RS01935 408980..409639 - 660 WP_000831300.1 hypothetical protein -
PXV45_RS01940 409699..410841 - 1143 WP_001176859.1 glycerate kinase -
PXV45_RS01945 411108..411494 + 387 WP_000779355.1 flippase GtxA -
PXV45_RS01950 411628..411735 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 411752..411812 - 61 - - Antitoxin
PXV45_RS01955 412439..414202 + 1764 WP_001064818.1 ABC transporter ATP-binding protein -
PXV45_RS01960 414227..415960 + 1734 WP_000486511.1 ABC transporter ATP-binding protein -
PXV45_RS01965 416191..416358 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T273754 WP_000482647.1 NZ_CP119109:411628-411735 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT273754 NZ_CP119109:c411812-411752 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References