Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 1926094..1926722 Replicon chromosome
Accession NZ_CP119106
Organism Isoptericola sp. AK164

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag PO879_RS08930 Protein ID WP_278237496.1
Coordinates 1926405..1926722 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name HigA2 Uniprot ID -
Locus tag PO879_RS08925 Protein ID WP_278234562.1
Coordinates 1926094..1926405 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PO879_RS08905 1921177..1921941 + 765 WP_278234558.1 anti-sigma factor -
PO879_RS08910 1922085..1923125 + 1041 WP_278234559.1 NAD(P)-dependent alcohol dehydrogenase -
PO879_RS08915 1923271..1924914 + 1644 WP_278234560.1 FAD-dependent oxidoreductase -
PO879_RS08920 1925304..1925699 + 396 WP_278234561.1 VOC family protein -
PO879_RS08925 1926094..1926405 - 312 WP_278234562.1 helix-turn-helix transcriptional regulator Antitoxin
PO879_RS08930 1926405..1926722 - 318 WP_278237496.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PO879_RS08935 1927035..1927556 - 522 WP_278234563.1 Imm26 family immunity protein -
PO879_RS08945 1928217..1929083 - 867 WP_278234564.1 aminotransferase class IV -
PO879_RS08950 1929089..1929700 - 612 WP_278234565.1 dihydrofolate reductase family protein -
PO879_RS08955 1929731..1930861 - 1131 WP_278234566.1 chorismate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-90)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11761.47 Da        Isoelectric Point: 9.9977

>T273745 WP_278237496.1 NZ_CP119106:c1926722-1926405 [Isoptericola sp. AK164]
MALDEDSYAQVVAAIELLQQSGPSLGRPLVDTVKASRHKNMKELRPGSSGRSELRVLFAFDPGRRAIMLVAGDKAGNWKR
WYKKSIPEADDLLDTHIRRLKTEGE

Download         Length: 318 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11599.32 Da        Isoelectric Point: 6.4780

>AT273745 WP_278234562.1 NZ_CP119106:c1926405-1926094 [Isoptericola sp. AK164]
MEMALDLDDVLAKRPVDRELVDAHKGRMLSEVRAYRLRELREALGLTQLELAQRIGVGQRQVSKIEHGDIDNAKVGTVRK
YLEAVGGDLAIEYVTTDRRVQVA

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References