Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) holin-SprF1/-
Location 1754764..1755134 Replicon chromosome
Accession NZ_CP118982
Organism Staphylococcus equorum strain DSM 20674

Toxin (Protein)


Gene name holin Uniprot ID A0A1E5TGW5
Locus tag PYW44_RS08460 Protein ID WP_021338679.1
Coordinates 1754764..1754985 (-) Length 74 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 1755036..1755134 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYW44_RS08435 1750136..1750693 + 558 WP_021338684.1 GNAT family protein -
PYW44_RS08440 1750755..1752638 - 1884 WP_069812506.1 glycosyltransferase family 2 protein -
PYW44_RS08445 1752945..1753649 - 705 WP_256092540.1 glycerophosphodiester phosphodiesterase family protein -
PYW44_RS08450 1754087..1754194 - 108 WP_021338681.1 putative holin-like toxin -
PYW44_RS08455 1754493..1754609 - 117 WP_165349553.1 putative holin-like toxin -
PYW44_RS08460 1754764..1754985 - 222 WP_021338679.1 phage holin Toxin
- 1755036..1755134 + 99 - - Antitoxin
PYW44_RS08470 1755823..1756332 - 510 WP_002507954.1 metallophosphoesterase -
PYW44_RS08475 1756332..1756913 - 582 WP_069812512.1 XTP/dITP diphosphatase -
PYW44_RS08480 1756931..1757725 - 795 WP_002507956.1 glutamate racemase -
PYW44_RS08485 1758001..1758822 - 822 WP_002507957.1 succinate dehydrogenase iron-sulfur subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Holin

(7-59)


Sequences

Toxin        


Download         Length: 74 a.a.        Molecular weight: 8279.78 Da        Isoelectric Point: 4.8018

>T273695 WP_021338679.1 NZ_CP118982:c1754985-1754764 [Staphylococcus equorum]
MDVKVTVIVRVLSLILVLVNQWLSNKEVSPIPVDESTLMTIAVALITMWKDNPFTDAAKGSFFKSYTYQLEIF

Download         Length: 222 bp

Antitoxin


Download         Length: 99 bp

>AT273695 NZ_CP118982:1755036-1755134 [Staphylococcus equorum]
ATTTGATAATATTTATATGTTGTGTTAATTTATATATAGAAAAAGGGCAACACACCATACGTGTATCGCCCCAATGAGCC
CGTTAAAAAGACGGTGGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1E5TGW5

Antitoxin

Download structure file

References