Detailed information of TA system TA273693

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 977331..977590
• Replicon: chromosome
• Accession: NZ_CP118982
• Organism: Staphylococcus equorum strain DSM 20674

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: PYW44_RS04635
• Protein ID: WP_002511402.1
• Coordinates: 977331..977438 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	977428..977590 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PYW44_RS04605	972563..973435	+	873	WP_002507156.1	ABC transporter ATP-binding protein	-
PYW44_RS04610	973435..974163	+	729	WP_002507157.1	ABC transporter permease subunit	-
PYW44_RS04615	974246..974806	-	561	WP_002507158.1	thioredoxin family protein	-
PYW44_RS04620	975022..975462	+	441	WP_231111012.1	hypothetical protein	-
PYW44_RS04625	975542..976117	+	576	WP_002507160.1	DUF1700 domain-containing protein	-
PYW44_RS04630	976114..976965	+	852	WP_021339982.1	DUF4097 family beta strand repeat-containing protein	-
PYW44_RS04635	977331..977438	+	108	WP_002511402.1	putative holin-like toxin	Toxin
-	977428..977590	-	163	-	-	Antitoxin
PYW44_RS04640	977726..977896	-	171	WP_021339983.1	tyrosine-type recombinase/integrase	-
PYW44_RS04645	978204..979244	-	1041	WP_021339984.1	C45 family autoproteolytic acyltransferase/hydolase	-
PYW44_RS04650	979739..979909	+	171	WP_002507168.1	hypothetical protein	-
PYW44_RS04655	980534..980944	-	411	WP_002507169.1	YolD-like family protein	-
PYW44_RS04660	981121..982158	+	1038	WP_021339833.1	lactonase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (4-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3756.72 Da
• Isoelectric Point: 10.4997

>T273693 WP_002511402.1 NZ_CP118982:977331-977438 [Staphylococcus equorum]
VVPIVEALHLMLGFGTFIVTLLGLVVAIVKLSHKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 163 bp

>AT273693 NZ_CP118982:c977590-977428 [Staphylococcus equorum]
ATTTGATAATATTTTTATGTTGTGGTAATTTATATATAGAAAAAGGGCAACACACCATAAGTGTATCGCCCTAATGAGCC
CGTTAAAAAGACGGTGGCTGGAATTTAATAATGATTAAATAATCATCTCATCCTCGCCAAAGTTAGAGATGGTTATTTTT
TAT

Structures

Antitoxin