Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 48564..49083 Replicon chromosome
Accession NZ_CP118973
Organism Staphylococcus warneri strain DSM 20316

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PYW39_RS00215 Protein ID WP_047210570.1
Coordinates 48811..49083 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A2T4PYE3
Locus tag PYW39_RS00210 Protein ID WP_002466398.1
Coordinates 48564..48818 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYW39_RS00195 44081..45403 + 1323 WP_103286081.1 PrsW family glutamic-type intramembrane protease -
PYW39_RS00200 45554..45991 + 438 WP_103286080.1 hypothetical protein -
PYW39_RS00205 46118..48319 - 2202 WP_103286079.1 YSIRK-type signal peptide-containing protein -
PYW39_RS00210 48564..48818 + 255 WP_002466398.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PYW39_RS00215 48811..49083 + 273 WP_047210570.1 Txe/YoeB family addiction module toxin Toxin
PYW39_RS00220 49476..50846 + 1371 WP_002450206.1 citrate:proton symporter -
PYW39_RS00225 50939..51577 - 639 WP_103286078.1 NAD(P)H-dependent oxidoreductase -
PYW39_RS00230 51803..52669 - 867 WP_103286077.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10861.64 Da        Isoelectric Point: 9.9029

>T273674 WP_047210570.1 NZ_CP118973:48811-49083 [Staphylococcus warneri]
MSRLNILFTPDAFEDYKYWQIHDKKLLKKINHLIKCINRNGPLEGEGKPEALKGNFKGYYSRRINFEHRLVYKVHDSEII
IVSCKYHYFK

Download         Length: 273 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9345.27 Da        Isoelectric Point: 4.0334

>AT273674 WP_002466398.1 NZ_CP118973:48564-48818 [Staphylococcus warneri]
MAIVSYSIARKNFRSLIDKVNNDSDAVTITTNDSNAVLISESDYNAMMETLYLQQSPANAQHLAKSIEDAERGNTIEVDL
ESYE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2T4PYE3

References