Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 1960933..1961518 Replicon chromosome
Accession NZ_CP118892
Organism Acinetobacter sp. TAC-1

Toxin (Protein)


Gene name higB Uniprot ID A0A077KZ82
Locus tag PYV58_RS09115 Protein ID WP_034617593.1
Coordinates 1960933..1961253 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PYV58_RS09120 Protein ID WP_034617591.1
Coordinates 1961246..1961518 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYV58_RS09100 (PYV58_09100) 1956257..1957867 - 1611 WP_034617274.1 pitrilysin family protein -
PYV58_RS09105 (PYV58_09105) 1957881..1959275 - 1395 WP_034617275.1 pitrilysin family protein -
PYV58_RS09110 (PYV58_09110) 1959452..1960558 + 1107 WP_034617276.1 signal recognition particle-docking protein FtsY -
PYV58_RS09115 (PYV58_09115) 1960933..1961253 + 321 WP_034617593.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PYV58_RS09120 (PYV58_09120) 1961246..1961518 + 273 WP_034617591.1 NadS family protein Antitoxin
PYV58_RS09125 (PYV58_09125) 1962154..1962747 + 594 WP_034617589.1 nitroreductase family protein -
PYV58_RS09130 (PYV58_09130) 1963387..1965549 + 2163 WP_034617586.1 malate synthase G -
PYV58_RS09135 (PYV58_09135) 1965740..1966360 + 621 WP_004719624.1 2OG-Fe(II) oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(35-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-84)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12139.95 Da        Isoelectric Point: 8.0125

>T273525 WP_034617593.1 NZ_CP118892:1960933-1961253 [Acinetobacter sp. TAC-1]
MLFIETSIFTKQIKELVTDDEYRQLQQNLLVQPDKGDIVKNGGGIRKVRCAQGDKGKSGGIRVIYYWVSEDDHIFFLVAY
PKSVKDNLTDKETAILRQLVKEQLHG

Download         Length: 321 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10223.64 Da        Isoelectric Point: 7.2045

>AT273525 WP_034617591.1 NZ_CP118892:1961246-1961518 [Acinetobacter sp. TAC-1]
MDKNLFDDLVSSIKEAGEIKRQEIQASRVTELELPDIKAVREKTGLSQNEFAARLHISPRTLQNWEQGRRYPTGPAATLI
RILDTHPSLI

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A077KZ82

Antitoxin

Source ID Structure

References