273502

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 14045..14568 Replicon plasmid pML7049-1
Accession NZ_CP118843
Organism Staphylococcus epidermidis strain 7049

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PYH64_RS11770 Protein ID WP_282872335.1
Coordinates 14302..14568 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PYH64_RS11765 Protein ID WP_121826844.1
Coordinates 14045..14302 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH64_RS11735 (PYH64_11735) 9679..10062 - 384 WP_124726245.1 hypothetical protein -
PYH64_RS11740 (PYH64_11740) 10064..10342 - 279 WP_203401249.1 hypothetical protein -
PYH64_RS11745 (PYH64_11745) 10916..11320 - 405 WP_282872334.1 hypothetical protein -
PYH64_RS11750 (PYH64_11750) 11741..12403 - 663 WP_124726243.1 hypothetical protein -
PYH64_RS11755 (PYH64_11755) 12756..13154 - 399 WP_049387923.1 YolD-like family protein -
PYH64_RS11760 (PYH64_11760) 13314..13871 + 558 WP_049387924.1 hypothetical protein -
PYH64_RS11765 (PYH64_11765) 14045..14302 + 258 WP_121826844.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PYH64_RS11770 (PYH64_11770) 14302..14568 + 267 WP_282872335.1 Txe/YoeB family addiction module toxin Toxin
PYH64_RS11775 (PYH64_11775) 14585..14755 + 171 WP_016898857.1 hypothetical protein -
PYH64_RS11780 (PYH64_11780) 15166..15804 - 639 WP_282872336.1 hypothetical protein -
PYH64_RS11785 (PYH64_11785) 16095..16190 + 96 Protein_20 transposase -
PYH64_RS11790 (PYH64_11790) 16475..17023 + 549 WP_031893297.1 recombinase family protein -
PYH64_RS11795 (PYH64_11795) 17048..17818 + 771 WP_064774971.1 CPBP family glutamic-type intramembrane protease -
PYH64_RS11800 (PYH64_11800) 17852..18298 - 447 WP_064774972.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..45478 45478


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10711.38 Da        Isoelectric Point: 10.3472

>T273502 WP_282872335.1 NZ_CP118843:14302-14568 [Staphylococcus epidermidis]
MAKYKINIKNSAKTDLKKIKRSHLQEQFLKIVEILKYDPYQQSQSFEKLRPKHLGRYSRRINHQHRVVYTIDEENKEVLI
LAAWSHYE

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9982.16 Da        Isoelectric Point: 5.1750

>AT273502 WP_121826844.1 NZ_CP118843:14045-14302 [Staphylococcus epidermidis]
MKSKTPTEARKDFYQLLKRVNSDHKPVYIEGKNDESNAVIIGMEDWRSIKETIYLEATGTMQKVREREQDNSGYTNIDDI
DWARL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References