Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2480092..2480276 Replicon chromosome
Accession NZ_CP118835
Organism Staphylococcus aureus strain 7051

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag PYH51_RS12425 Protein ID WP_000482647.1
Coordinates 2480169..2480276 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2480092..2480152 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH51_RS12410 2475543..2475710 - 168 WP_001790576.1 hypothetical protein -
PYH51_RS12415 2475941..2477674 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
PYH51_RS12420 2477699..2479462 - 1764 WP_006191000.1 ABC transporter ATP-binding protein -
- 2480092..2480152 + 61 - - Antitoxin
PYH51_RS12425 2480169..2480276 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
PYH51_RS12430 2480410..2480796 - 387 WP_000779360.1 flippase GtxA -
PYH51_RS12435 2481064..2482206 + 1143 WP_001176863.1 glycerate kinase -
PYH51_RS12440 2482266..2482925 + 660 WP_000831298.1 membrane protein -
PYH51_RS12445 2483107..2484318 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
PYH51_RS12450 2484441..2484914 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T273494 WP_000482647.1 NZ_CP118835:c2480276-2480169 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT273494 NZ_CP118835:2480092-2480152 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References