Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2200288..2200504 Replicon chromosome
Accession NZ_CP118835
Organism Staphylococcus aureus strain 7051

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag PYH51_RS10955 Protein ID WP_001802298.1
Coordinates 2200400..2200504 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2200288..2200343 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH51_RS10930 2196425..2197090 - 666 WP_045177733.1 SDR family oxidoreductase -
PYH51_RS10935 2197242..2197562 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PYH51_RS10940 2197564..2198544 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
PYH51_RS10945 2198810..2199901 + 1092 WP_045177732.1 lytic regulatory protein -
- 2200288..2200343 + 56 - - Antitoxin
PYH51_RS10955 2200400..2200504 - 105 WP_001802298.1 hypothetical protein Toxin
PYH51_RS10960 2201184..2201342 + 159 WP_001792784.1 hypothetical protein -
PYH51_RS10965 2202001..2202858 - 858 WP_045177730.1 HAD family hydrolase -
PYH51_RS10970 2202925..2203707 - 783 WP_045177727.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T273491 WP_001802298.1 NZ_CP118835:c2200504-2200400 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT273491 NZ_CP118835:2200288-2200343 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References