Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/- |
| Location | 2051303..2051717 | Replicon | chromosome |
| Accession | NZ_CP118835 | ||
| Organism | Staphylococcus aureus strain 7051 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | PYH51_RS10145 | Protein ID | WP_001826875.1 |
| Coordinates | 2051466..2051717 (-) | Length | 84 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | PYH51_RS10140 | Protein ID | WP_000028424.1 |
| Coordinates | 2051303..2051476 (-) | Length | 58 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PYH51_RS10080 (2047351) | 2047351..2047818 | - | 468 | WP_000919026.1 | phage terminase small subunit P27 family | - |
| PYH51_RS10085 (2047947) | 2047947..2048291 | - | 345 | WP_000817289.1 | HNH endonuclease | - |
| PYH51_RS10090 (2048307) | 2048307..2048759 | - | 453 | WP_000406191.1 | nucleoside triphosphate pyrophosphohydrolase family protein | - |
| PYH51_RS10095 (2048874) | 2048874..2049335 | - | 462 | WP_000282756.1 | hypothetical protein | - |
| PYH51_RS10100 (2049358) | 2049358..2049558 | - | 201 | WP_001570807.1 | DUF1514 family protein | - |
| PYH51_RS10105 (2049558) | 2049558..2049683 | - | 126 | WP_031783376.1 | transcriptional regulator | - |
| PYH51_RS10110 (2049676) | 2049676..2049879 | - | 204 | WP_001072793.1 | hypothetical protein | - |
| PYH51_RS10115 (2049880) | 2049880..2050071 | - | 192 | Protein_1954 | hypothetical protein | - |
| PYH51_RS10120 (2050068) | 2050068..2050274 | - | 207 | WP_000195826.1 | DUF1381 domain-containing protein | - |
| PYH51_RS10125 (2050311) | 2050311..2050844 | - | 534 | WP_025920701.1 | dUTP diphosphatase | - |
| PYH51_RS10130 (2050859) | 2050859..2051020 | - | 162 | WP_000889679.1 | hypothetical protein | - |
| PYH51_RS10135 (2051021) | 2051021..2051302 | - | 282 | WP_000454993.1 | hypothetical protein | - |
| PYH51_RS10140 (2051303) | 2051303..2051476 | - | 174 | WP_000028424.1 | hypothetical protein | Antitoxin |
| PYH51_RS10145 (2051466) | 2051466..2051717 | - | 252 | WP_001826875.1 | DUF1024 family protein | Toxin |
| PYH51_RS10150 (2051732) | 2051732..2051974 | - | 243 | WP_000131389.1 | SAV1978 family virulence-associated passenger protein | - |
| PYH51_RS10155 (2051978) | 2051978..2052346 | - | 369 | WP_016028254.1 | SA1788 family PVL leukocidin-associated protein | - |
| PYH51_RS10160 (2052359) | 2052359..2052763 | - | 405 | WP_000401978.1 | RusA family crossover junction endodeoxyribonuclease | - |
| PYH51_RS10165 (2052772) | 2052772..2052990 | - | 219 | WP_000338527.1 | hypothetical protein | - |
| PYH51_RS10170 (2052997) | 2052997..2053890 | - | 894 | WP_000148335.1 | DnaD domain-containing protein | - |
| PYH51_RS10175 (2053920) | 2053920..2054390 | - | 471 | WP_000934760.1 | single-stranded DNA-binding protein | - |
| PYH51_RS10180 (2054391) | 2054391..2055008 | - | 618 | WP_071621397.1 | MBL fold metallo-hydrolase | - |
| PYH51_RS10185 (2055089) | 2055089..2056009 | - | 921 | WP_000138475.1 | recombinase RecT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | scn / sak / sea / hlb / groEL | 2022918..2076572 | 53654 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|