Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1824052..1824234 Replicon chromosome
Accession NZ_CP118835
Organism Staphylococcus aureus strain 7051

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag PYH51_RS08680 Protein ID WP_001801861.1
Coordinates 1824052..1824147 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1824175..1824234 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH51_RS08645 1819722..1820348 + 627 WP_045177256.1 hypothetical protein -
PYH51_RS08650 1820389..1820730 + 342 WP_045177258.1 DUF3969 family protein -
PYH51_RS08655 1820831..1821403 + 573 WP_045177260.1 hypothetical protein -
PYH51_RS08660 1821601..1822229 - 629 Protein_1702 ImmA/IrrE family metallo-endopeptidase -
PYH51_RS08665 1822532..1822708 - 177 WP_000375477.1 hypothetical protein -
PYH51_RS08670 1822719..1823102 - 384 WP_000070811.1 hypothetical protein -
PYH51_RS08675 1823706..1823849 - 144 WP_001549059.1 transposase -
PYH51_RS08680 1824052..1824147 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1824175..1824234 - 60 - - Antitoxin
PYH51_RS08685 1824270..1824371 + 102 WP_001791893.1 hypothetical protein -
PYH51_RS08690 1824349..1824525 - 177 Protein_1708 transposase -
PYH51_RS08695 1824719..1825096 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - lukD / hlgA 1817162..1901183 84021


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T273482 WP_001801861.1 NZ_CP118835:1824052-1824147 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT273482 NZ_CP118835:c1824234-1824175 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References