Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2480095..2480279 Replicon chromosome
Accession NZ_CP118832
Organism Staphylococcus aureus strain 7053

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag PYH65_RS12430 Protein ID WP_000482647.1
Coordinates 2480172..2480279 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2480095..2480155 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH65_RS12415 2475546..2475713 - 168 WP_001790576.1 hypothetical protein -
PYH65_RS12420 2475944..2477677 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
PYH65_RS12425 2477702..2479465 - 1764 WP_006191000.1 ABC transporter ATP-binding protein -
- 2480095..2480155 + 61 - - Antitoxin
PYH65_RS12430 2480172..2480279 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
PYH65_RS12435 2480413..2480799 - 387 WP_000779360.1 flippase GtxA -
PYH65_RS12440 2481067..2482209 + 1143 WP_001176863.1 glycerate kinase -
PYH65_RS12445 2482269..2482928 + 660 WP_000831298.1 membrane protein -
PYH65_RS12450 2483110..2484321 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
PYH65_RS12455 2484444..2484917 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T273479 WP_000482647.1 NZ_CP118832:c2480279-2480172 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT273479 NZ_CP118832:2480095-2480155 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References