Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2200291..2200507 Replicon chromosome
Accession NZ_CP118832
Organism Staphylococcus aureus strain 7053

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag PYH65_RS10960 Protein ID WP_001802298.1
Coordinates 2200403..2200507 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2200291..2200346 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH65_RS10935 2196428..2197093 - 666 WP_045177733.1 SDR family oxidoreductase -
PYH65_RS10940 2197245..2197565 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PYH65_RS10945 2197567..2198547 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
PYH65_RS10950 2198813..2199904 + 1092 WP_045177732.1 lytic regulatory protein -
- 2200291..2200346 + 56 - - Antitoxin
PYH65_RS10960 2200403..2200507 - 105 WP_001802298.1 hypothetical protein Toxin
PYH65_RS10965 2201187..2201345 + 159 WP_001792784.1 hypothetical protein -
PYH65_RS10970 2202004..2202861 - 858 WP_045177730.1 HAD family hydrolase -
PYH65_RS10975 2202928..2203710 - 783 WP_045177727.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T273476 WP_001802298.1 NZ_CP118832:c2200507-2200403 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT273476 NZ_CP118832:2200291-2200346 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References