Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2511296..2511819 Replicon chromosome
Accession NZ_CP118830
Organism Staphylococcus aureus strain 7054

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PYH54_RS12565 Protein ID WP_045177693.1
Coordinates 2511296..2511562 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PYH54_RS12570 Protein ID WP_086095185.1
Coordinates 2511562..2511819 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH54_RS12545 (2506602) 2506602..2507789 - 1188 WP_045177690.1 MFS transporter -
PYH54_RS12550 (2508185) 2508185..2508961 - 777 WP_000072151.1 iron export ABC transporter permease subunit FetB -
PYH54_RS12555 (2508954) 2508954..2509616 - 663 WP_045177691.1 ATP-binding cassette domain-containing protein -
PYH54_RS12560 (2509864) 2509864..2510940 - 1077 WP_001076673.1 M42 family metallopeptidase -
PYH54_RS12565 (2511296) 2511296..2511562 - 267 WP_045177693.1 Txe/YoeB family addiction module toxin Toxin
PYH54_RS12570 (2511562) 2511562..2511819 - 258 WP_086095185.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PYH54_RS12575 (2512179) 2512179..2512634 + 456 WP_000732090.1 YehR family lipoprotein -
PYH54_RS12580 (2512802) 2512802..2514379 - 1578 WP_282872635.1 FMN-binding glutamate synthase family protein -
PYH54_RS12585 (2514574) 2514574..2515323 + 750 WP_000072443.1 CPBP family lipoprotein N-acylation protein LnsB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(26-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10684.35 Da        Isoelectric Point: 10.1384

>T273465 WP_045177693.1 NZ_CP118830:c2511562-2511296 [Staphylococcus aureus]
MSNYTVKIKNSAKLDLKKIKHPYLKKSFLEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLI
LSAWSHYD

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9704.75 Da        Isoelectric Point: 4.2813

>AT273465 WP_086095185.1 NZ_CP118830:c2511819-2511562 [Staphylococcus aureus]
MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETMYLVSTGTMDKVREREKGNSGTTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References