Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2200292..2200508 Replicon chromosome
Accession NZ_CP118830
Organism Staphylococcus aureus strain 7054

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag PYH54_RS10955 Protein ID WP_001802298.1
Coordinates 2200404..2200508 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2200292..2200347 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PYH54_RS10930 2196429..2197094 - 666 WP_045177733.1 SDR family oxidoreductase -
PYH54_RS10935 2197246..2197566 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
PYH54_RS10940 2197568..2198548 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
PYH54_RS10945 2198814..2199905 + 1092 WP_045177732.1 lytic regulatory protein -
- 2200292..2200347 + 56 - - Antitoxin
PYH54_RS10955 2200404..2200508 - 105 WP_001802298.1 hypothetical protein Toxin
PYH54_RS10960 2201188..2201346 + 159 WP_001792784.1 hypothetical protein -
PYH54_RS10965 2202005..2202862 - 858 WP_045177730.1 HAD family hydrolase -
PYH54_RS10970 2202929..2203711 - 783 WP_045177727.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T273461 WP_001802298.1 NZ_CP118830:c2200508-2200404 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT273461 NZ_CP118830:2200292-2200347 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References