Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 5958875..5959692 Replicon chromosome
Accession NZ_CP118775
Organism Delftia tsuruhatensis strain ULwDis3

Toxin (Protein)


Gene name yhaV Uniprot ID A0A072THA9
Locus tag PW274_RS27825 Protein ID WP_043790975.1
Coordinates 5959201..5959692 (+) Length 164 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag PW274_RS27820 Protein ID WP_016448384.1
Coordinates 5958875..5959204 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PW274_RS27795 (PW274_27795) 5954083..5954358 - 276 WP_047327871.1 type II toxin-antitoxin system ParD family antitoxin -
PW274_RS27800 (PW274_27800) 5954425..5955258 - 834 WP_126311033.1 helix-turn-helix transcriptional regulator -
PW274_RS27805 (PW274_27805) 5955329..5955991 + 663 WP_126311034.1 pyridoxamine 5'-phosphate oxidase family protein -
PW274_RS27810 (PW274_27810) 5956019..5956414 + 396 WP_126311035.1 hypothetical protein -
PW274_RS27815 (PW274_27815) 5956538..5958778 + 2241 WP_126311036.1 TonB-dependent receptor -
PW274_RS27820 (PW274_27820) 5958875..5959204 + 330 WP_016448384.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
PW274_RS27825 (PW274_27825) 5959201..5959692 + 492 WP_043790975.1 type II toxin-antitoxin system YhaV family toxin Toxin
PW274_RS27830 (PW274_27830) 5959707..5960219 - 513 WP_016448386.1 MgtC/SapB family protein -
PW274_RS27835 (PW274_27835) 5960334..5961731 - 1398 WP_017406579.1 chloride channel protein -
PW274_RS27840 (PW274_27840) 5962006..5962335 - 330 WP_013800515.1 DHCW motif cupin fold protein -
PW274_RS27845 (PW274_27845) 5962399..5963196 - 798 WP_126311037.1 precorrin-6A synthase (deacetylating) -
PW274_RS27850 (PW274_27850) 5963193..5964071 - 879 WP_126311038.1 precorrin-4 C(11)-methyltransferase -
PW274_RS27855 (PW274_27855) 5964068..5964565 - 498 WP_126311039.1 cobalamin biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-107)


Sequences

Toxin        


Download         Length: 164 a.a.        Molecular weight: 18801.33 Da        Isoelectric Point: 9.9304

>T273436 WP_043790975.1 NZ_CP118775:5959201-5959692 [Delftia tsuruhatensis]
MSAVPPAPLRIHGWTVFMHPLFLAQLQALSHEVEGLKTKDPGGYTRKNATKRLAAIRKLAFDVIPQDPTRPDYRQGHTLG
EEHKHWFRARFFQQYRLFFRFHAPSKIIVFAWVNDEDTRRAYEGSDDAYRVFRKMLANGHPPGDWDSLLAQAESPPPDSQ
PHA

Download         Length: 492 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12062.53 Da        Isoelectric Point: 4.1858

>AT273436 WP_016448384.1 NZ_CP118775:5958875-5959204 [Delftia tsuruhatensis]
MFSTLEAESTLTDRYQTTIPEAVRRALHLSKRDRIHYTILPGGEVVLSRADSAEDADPVLGQFLGFLAQDMAAHPERLQT
MDARLAQQIQALTEGIEVDLDAPLLADDE

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A072THA9

Antitoxin

Source ID Structure

References