Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2762215..2762552 Replicon chromosome
Accession NZ_CP118755
Organism Enterococcus faecalis strain W5

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag PWA41_RS13380 Protein ID WP_016619108.1
Coordinates 2762215..2762358 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2762290..2762552 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWA41_RS13365 (2757931) 2757931..2758563 - 633 WP_002358972.1 RloB family protein -
PWA41_RS13370 (2758572) 2758572..2759867 - 1296 WP_275016500.1 AAA family ATPase -
PWA41_RS13375 (2760329) 2760329..2761945 + 1617 WP_153246973.1 phosphatase PAP2/LCP family protein -
- (2762041) 2762041..2762104 - 64 NuclAT_8 - -
PWA41_RS13380 (2762215) 2762215..2762358 + 144 WP_016619108.1 putative holin-like toxin Toxin
- (2762502) 2762502..2762551 + 50 NuclAT_9 - -
- (2762290) 2762290..2762552 - 263 NuclAT_7 - Antitoxin
PWA41_RS13385 (2762553) 2762553..2767244 - 4692 WP_153246974.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5191.13 Da        Isoelectric Point: 8.6626

>T273414 WP_016619108.1 NZ_CP118755:2762215-2762358 [Enterococcus faecalis]
MNVSTKTYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT273414 NZ_CP118755:c2762552-2762290 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGATGATCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References