Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 4730615..4731157 Replicon chromosome
Accession NZ_CP118631
Organism Mucilaginibacter sp. SJ

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MusilaSJ_RS19575 Protein ID WP_274986542.1
Coordinates 4730882..4731157 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MusilaSJ_RS19570 Protein ID WP_274986541.1
Coordinates 4730615..4730878 (+) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MusilaSJ_RS19545 (MusilaSJ_19545) 4726626..4727321 + 696 WP_274986536.1 DUF4397 domain-containing protein -
MusilaSJ_RS19550 (MusilaSJ_19550) 4727330..4728070 + 741 WP_274986537.1 DUF4397 domain-containing protein -
MusilaSJ_RS19555 (MusilaSJ_19555) 4728116..4728766 + 651 WP_274986538.1 VTT domain-containing protein -
MusilaSJ_RS19560 (MusilaSJ_19560) 4728790..4729467 - 678 WP_274986539.1 hypothetical protein -
MusilaSJ_RS19565 (MusilaSJ_19565) 4729565..4730527 - 963 WP_274986540.1 zinc dependent phospholipase C family protein -
MusilaSJ_RS19570 (MusilaSJ_19570) 4730615..4730878 + 264 WP_274986541.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MusilaSJ_RS19575 (MusilaSJ_19575) 4730882..4731157 + 276 WP_274986542.1 Txe/YoeB family addiction module toxin Toxin
MusilaSJ_RS19580 (MusilaSJ_19580) 4731216..4731974 - 759 WP_274986543.1 class I SAM-dependent methyltransferase -
MusilaSJ_RS19585 (MusilaSJ_19585) 4732221..4732475 + 255 WP_090529771.1 30S ribosomal protein S20 -
MusilaSJ_RS19590 (MusilaSJ_19590) 4732560..4733258 + 699 WP_274986544.1 DNA repair protein RadC -
MusilaSJ_RS19595 (MusilaSJ_19595) 4733401..4735800 + 2400 WP_274986545.1 phenylalanine--tRNA ligase subunit beta -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-89)

Antitoxin

(1-75)


Sequences


Toxin        


Download         Length: 92 a.a.        Molecular weight: 10841.30 Da        Isoelectric Point: 7.9025

>T273330 WP_274986542.1 NZ_CP118631:4730882-4731157 [Mucilaginibacter sp. SJ]
MITEFTQHGWNDFEYWLENDLEVVEKIRELIKSIKQTPFKGLGKPEPLRHSLKGYWSRRITGEHRLVYQVSGTKGDDQRC
SIVQCRFHYGE

Download         Length: 276 bp


Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9757.98 Da        Isoelectric Point: 5.8063

>AT273330 WP_274986541.1 NZ_CP118631:4730615-4730878 [Mucilaginibacter sp. SJ]
MKVLTISSLRSKMKSYFDVVSNNQDVIVVPRNNNDEDAVVIMSIKEYNSLTETGHLLSTAANSRRLEESIDQLKSGKTIT
YDFDSGK

Download         Length: 264 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References