Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 6243..6898 Replicon chromosome
Accession NZ_CP118629
Organism Pantoea dispersa strain VWJL.P1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PWF83_RS00030 Protein ID WP_058758198.1
Coordinates 6545..6898 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PWF83_RS00025 Protein ID WP_058770729.1
Coordinates 6243..6548 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWF83_RS00010 (PWF83_00010) 1410..2510 + 1101 WP_010617831.1 DNA polymerase III subunit beta -
PWF83_RS00015 (PWF83_00015) 2690..3775 + 1086 WP_058758201.1 DNA replication/repair protein RecF -
PWF83_RS00020 (PWF83_00020) 3793..6201 + 2409 WP_058758200.1 DNA topoisomerase (ATP-hydrolyzing) subunit B -
PWF83_RS00025 (PWF83_00025) 6243..6548 - 306 WP_058770729.1 helix-turn-helix transcriptional regulator Antitoxin
PWF83_RS00030 (PWF83_00030) 6545..6898 - 354 WP_058758198.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PWF83_RS00035 (PWF83_00035) 7105..7914 + 810 WP_159377266.1 sugar-phosphatase -
PWF83_RS00040 (PWF83_00040) 8131..8829 + 699 WP_058770730.1 FadR/GntR family transcriptional regulator -
PWF83_RS00045 (PWF83_00045) 8826..9704 + 879 WP_058758195.1 2-dehydro-3-deoxygalactonokinase -
PWF83_RS00050 (PWF83_00050) 9688..10305 + 618 WP_021506907.1 2-dehydro-3-deoxy-6-phosphogalactonate aldolase -
PWF83_RS00055 (PWF83_00055) 10302..11450 + 1149 WP_058758194.1 galactonate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-87)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13609.64 Da        Isoelectric Point: 9.6733

>T273316 WP_058758198.1 NZ_CP118629:c6898-6545 [Pantoea dispersa]
MWEIIFTDTFREWLRAQDNKLKKRIAAALLNLQHYGPLLPRPYADTVNGSRFHNMKELRIQYAGQPIRALYAFDTQRKAV
ILCAGNKSGDKQFYARMICLADQLFTAYLNNAEENHS

Download         Length: 354 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11303.04 Da        Isoelectric Point: 4.3253

>AT273316 WP_058770729.1 NZ_CP118629:c6548-6243 [Pantoea dispersa]
MNDLQKFIESEFTEAEQTDIQLMADELILETGLQLLREELALSQRTVAEAMGVKQPRITQIEQGGADQRLITIKRYIEAM
GGKLSLLIEMPDGSGGRILRV

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References