Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 5655678..5656186 Replicon chromosome
Accession NZ_CP118614
Organism Nocardiopsis sp. DZFXJ 01

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PV789_RS24655 Protein ID WP_274974756.1
Coordinates 5655926..5656186 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PV789_RS24650 Protein ID WP_274974755.1
Coordinates 5655678..5655929 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PV789_RS24625 (PV789_24625) 5651371..5652333 + 963 WP_274974750.1 fatty acid desaturase -
PV789_RS24630 (PV789_24630) 5652348..5653004 + 657 WP_274974751.1 TetR/AcrR family transcriptional regulator -
PV789_RS24635 (PV789_24635) 5653090..5653599 + 510 WP_274974752.1 MarR family transcriptional regulator -
PV789_RS24640 (PV789_24640) 5653854..5654837 + 984 WP_274974753.1 GDSL-type esterase/lipase family protein -
PV789_RS24645 (PV789_24645) 5654902..5655396 - 495 WP_274974754.1 glutathione peroxidase -
PV789_RS24650 (PV789_24650) 5655678..5655929 + 252 WP_274974755.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PV789_RS24655 (PV789_24655) 5655926..5656186 + 261 WP_274974756.1 Txe/YoeB family addiction module toxin Toxin
PV789_RS24660 (PV789_24660) 5656277..5658058 - 1782 WP_274974757.1 ABC-F family ATP-binding cassette domain-containing protein -
PV789_RS24665 (PV789_24665) 5658129..5659067 - 939 WP_274978246.1 sugar-binding domain-containing protein -
PV789_RS24670 (PV789_24670) 5659245..5660246 + 1002 WP_274974758.1 zinc-dependent alcohol dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5642147..5664489 22342


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10342.74 Da        Isoelectric Point: 9.7754

>T273313 WP_274974756.1 NZ_CP118614:5655926-5656186 [Nocardiopsis sp. DZFXJ 01]
MRLVWAQSAWEDYVWWQGQDHRILKRINALIKDIDRNGNDGMGKPEPLRHGFQGYWSRRITDEHRLVYKISGDEIRIAAC
RYHYGK

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9391.47 Da        Isoelectric Point: 4.1634

>AT273313 WP_274974755.1 NZ_CP118614:5655678-5655929 [Nocardiopsis sp. DZFXJ 01]
VKTMSYSESRANYAATLDSVVDDREEVVITRAGHEPVVMMALSEYETLKETAYLLRSPENVRRLVTAIEELESDQGIERD
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References