Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 967167..967690 Replicon chromosome
Accession NZ_CP118614
Organism Nocardiopsis sp. DZFXJ 01

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag PV789_RS04570 Protein ID WP_274976272.1
Coordinates 967433..967690 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PV789_RS04565 Protein ID WP_274976271.1
Coordinates 967167..967436 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PV789_RS04550 (PV789_04550) 963566..964264 + 699 WP_274976268.1 alpha/beta hydrolase -
PV789_RS04555 (PV789_04555) 964476..965456 - 981 WP_274976269.1 FkbM family methyltransferase -
PV789_RS04560 (PV789_04560) 965930..967015 + 1086 WP_274976270.1 redox-regulated ATPase YchF -
PV789_RS04565 (PV789_04565) 967167..967436 + 270 WP_274976271.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PV789_RS04570 (PV789_04570) 967433..967690 + 258 WP_274976272.1 Txe/YoeB family addiction module toxin Toxin
PV789_RS04575 (PV789_04575) 967733..968308 - 576 WP_274976273.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
PV789_RS04580 (PV789_04580) 968747..969697 + 951 WP_274976274.1 conjugal transfer protein -
PV789_RS04585 (PV789_04585) 969770..970087 + 318 WP_274976275.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-65)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10016.43 Da        Isoelectric Point: 7.4218

>T273310 WP_274976272.1 NZ_CP118614:967433-967690 [Nocardiopsis sp. DZFXJ 01]
VRRLVFEDHGWEGCTSWLKTDRKVLARINKLIGEIRRDPFTGIGEPEPLKYHLPGAWSRRIDDEHRPVHVVTEDEIVVIA
ARYHY

Download         Length: 258 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9650.81 Da        Isoelectric Point: 4.8307

>AT273310 WP_274976271.1 NZ_CP118614:967167-967436 [Nocardiopsis sp. DZFXJ 01]
MSITASEARRSLFPLIKKVNDDHDAIEIVSRHGNAVLVSAEDYAALREGAYLLRSPANARRLLKAYENALDGTGVSERGL
IGPDVEDAE

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References