273297

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 1157620..1158224 Replicon chromosome
Accession NZ_CP118607
Organism Pseudomonas sp. PSKL.D1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PVV54_RS05090 Protein ID WP_274908897.1
Coordinates 1157904..1158224 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PVV54_RS05085 Protein ID WP_274908896.1
Coordinates 1157620..1157907 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PVV54_RS05060 (PVV54_05060) 1153228..1154442 + 1215 WP_274908891.1 SAM-dependent methyltransferase -
PVV54_RS05065 (PVV54_05065) 1154601..1154879 + 279 WP_274908892.1 hypothetical protein -
PVV54_RS05070 (PVV54_05070) 1154882..1155391 + 510 WP_274908893.1 DNA-binding protein -
PVV54_RS05075 (PVV54_05075) 1155411..1156421 - 1011 WP_274908894.1 DUF4917 family protein -
PVV54_RS05080 (PVV54_05080) 1156534..1157601 + 1068 WP_274908895.1 glycerophosphodiester phosphodiesterase family protein -
PVV54_RS05085 (PVV54_05085) 1157620..1157907 - 288 WP_274908896.1 NadS family protein Antitoxin
PVV54_RS05090 (PVV54_05090) 1157904..1158224 - 321 WP_274908897.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PVV54_RS05095 (PVV54_05095) 1158381..1160078 - 1698 WP_274908898.1 SulP family inorganic anion transporter -
PVV54_RS05105 (PVV54_05105) 1160391..1161275 - 885 WP_274908899.1 alpha/beta fold hydrolase -
PVV54_RS05110 (PVV54_05110) 1161622..1162314 - 693 WP_274908900.1 16S rRNA pseudouridine(516) synthase -
PVV54_RS05115 (PVV54_05115) 1162349..1162573 - 225 WP_274908901.1 cysteine-rich CWC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-87)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12018.91 Da        Isoelectric Point: 9.4240

>T273297 WP_274908897.1 NZ_CP118607:c1158224-1157904 [Pseudomonas sp. PSKL.D1]
MLFIETPIFSRSVKELLDDEAYRLLQIQLMLSPDLGDLMEGTGGLRKVRVAANGRGKRGGARAIYYHFVASSQIAMLYIY
PKNEQSDLSTEQCKALKGVVEHWRRT

Download         Length: 321 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10712.32 Da        Isoelectric Point: 10.1758

>AT273297 WP_274908896.1 NZ_CP118607:c1157907-1157620 [Pseudomonas sp. PSKL.D1]
MSKFFEELLESVQQMDEIVQGKRPASRVFEIDALQVKAIRQSTGLSQARFAGMIDVQVATLRNWEQGRREPTGPAKALLR
AIRNDPDHVLKALAH

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References