Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 354146..354684 Replicon chromosome
Accession NZ_CP118542
Organism Salmonella sp. CVCC 1806

Toxin (Protein)


Gene name yafQ Uniprot ID M7RHM1
Locus tag PWA52_RS01610 Protein ID WP_001526148.1
Coordinates 354409..354684 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag PWA52_RS01605 Protein ID WP_269724490.1
Coordinates 354146..354406 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PWA52_RS01590 (350014) 350014..351567 + 1554 WP_045161971.1 TROVE domain-containing protein -
PWA52_RS01595 (351800) 351800..353014 + 1215 WP_001105533.1 RNA-splicing ligase RtcB -
PWA52_RS01600 (353018) 353018..354037 + 1020 Protein_316 RNA 3'-terminal phosphate cyclase -
PWA52_RS01605 (354146) 354146..354406 + 261 WP_269724490.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PWA52_RS01610 (354409) 354409..354684 + 276 WP_001526148.1 type II toxin-antitoxin system YafQ family toxin Toxin
PWA52_RS01615 (354772) 354772..357477 - 2706 WP_023136246.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10739.34 Da        Isoelectric Point: 8.8652

>T273194 WP_001526148.1 NZ_CP118542:354409-354684 [Salmonella sp. CVCC 1806]
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIEPDWILIYKITDECLR
FERTGTHADLF

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9474.81 Da        Isoelectric Point: 4.4734

>AT273194 WP_269724490.1 NZ_CP118542:354146-354406 [Salmonella sp. CVCC 1806]
MAANALVRARIDETLKDQAADVLAEMGLTISDLIRITLTRVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SM83

Antitoxin

Source ID Structure

References