Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3663561..3664213 Replicon chromosome
Accession NZ_CP118269
Organism Pantoea sp. Lij88

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PU624_RS21000 Protein ID WP_283546491.1
Coordinates 3663561..3663917 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PU624_RS21005 Protein ID WP_283546492.1
Coordinates 3663914..3664213 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PU624_RS20985 (PU624_20985) 3659289..3661073 - 1785 WP_283546488.1 GMC family oxidoreductase -
PU624_RS20990 (PU624_20990) 3661076..3661810 - 735 WP_283546489.1 gluconate 2-dehydrogenase subunit 3 family protein -
PU624_RS20995 (PU624_20995) 3662087..3663328 + 1242 WP_283546490.1 peptide antibiotic transporter SbmA -
PU624_RS21000 (PU624_21000) 3663561..3663917 + 357 WP_283546491.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PU624_RS21005 (PU624_21005) 3663914..3664213 + 300 WP_283546492.1 XRE family transcriptional regulator Antitoxin
PU624_RS21010 (PU624_21010) 3664371..3664580 - 210 WP_283546493.1 DUF1471 domain-containing protein -
PU624_RS21015 (PU624_21015) 3664793..3665980 - 1188 WP_283546494.1 MFS transporter -
PU624_RS21020 (PU624_21020) 3666086..3667051 + 966 WP_283546495.1 AraC family transcriptional regulator -
PU624_RS21025 (PU624_21025) 3667048..3668592 - 1545 WP_283546496.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-80)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 13816.90 Da        Isoelectric Point: 8.8339

>T272975 WP_283546491.1 NZ_CP118269:3663561-3663917 [Pantoea sp. Lij88]
MWTVLLSPRFESWLSEQEEALQEKMLADLGKLKVYGPDLPRPYADTLKGSQYKNMKELRVQFAGKPIRAFYAFDPVRQAI
VLCAGDKSHDKRFYIRMIRIADEEFSAWLAEQERKNNS

Download         Length: 357 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11054.87 Da        Isoelectric Point: 5.1881

>AT272975 WP_283546492.1 NZ_CP118269:3663914-3664213 [Pantoea sp. Lij88]
MRTLDDVIAGFSPESQARIKEMSDEMVLEVGLQMIREELQLSQKTLAEAMGVRQPAIAQIEQRGNEIKVATLKRYIEAMG
GKLSLDVELPTGKRVAFHI

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References