Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2773376..2773980 Replicon chromosome
Accession NZ_CP118269
Organism Pantoea sp. Lij88

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PU624_RS16785 Protein ID WP_283545891.1
Coordinates 2773376..2773687 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PU624_RS16790 Protein ID WP_150012147.1
Coordinates 2773687..2773980 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PU624_RS16765 (PU624_16765) 2768528..2769475 - 948 WP_283545887.1 ABC transporter ATP-binding protein -
PU624_RS16770 (PU624_16770) 2769468..2770643 - 1176 WP_283545888.1 ABC transporter permease -
PU624_RS16775 (PU624_16775) 2770647..2771558 - 912 WP_283545889.1 ABC transporter substrate-binding protein -
PU624_RS16780 (PU624_16780) 2771845..2773320 + 1476 WP_283545890.1 MFS transporter -
PU624_RS16785 (PU624_16785) 2773376..2773687 + 312 WP_283545891.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PU624_RS16790 (PU624_16790) 2773687..2773980 + 294 WP_150012147.1 NadS family protein Antitoxin
PU624_RS16795 (PU624_16795) 2774155..2774697 - 543 WP_283545892.1 isopentenyl-diphosphate Delta-isomerase -
PU624_RS16800 (PU624_16800) 2774844..2776739 - 1896 WP_283545893.1 methyl-accepting chemotaxis protein -
PU624_RS16805 (PU624_16805) 2776930..2778039 - 1110 WP_283545894.1 suppressor of fused domain protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-101)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12088.82 Da        Isoelectric Point: 8.3462

>T272972 WP_283545891.1 NZ_CP118269:2773376-2773687 [Pantoea sp. Lij88]
MLFIETPVFTEDVKELLSDDEYREFQQFMADNPYWGDVIQNTGGLRKVRWAAKGKGKRGGVRVIYYYKVSDSQIRLLLIY
KKGVQDDLSEDEKHLLRALNKGW

Download         Length: 312 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10829.50 Da        Isoelectric Point: 10.6057

>AT272972 WP_150012147.1 NZ_CP118269:2773687-2773980 [Pantoea sp. Lij88]
MDKKLFERLKESMTQMNEIVEGSREPSRETTVTAVKVKAIRNATGLSQSGFAKLISVNVDTLKNWEQGRREPTGPAKALL
RAIERDPKHVIPALADK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References