272970

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 1532115..1533445 Replicon chromosome
Accession NZ_CP118269
Organism Pantoea sp. Lij88

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag PU624_RS10840 Protein ID WP_283547620.1
Coordinates 1532115..1533137 (-) Length 341 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag PU624_RS10845 Protein ID WP_283547621.1
Coordinates 1533134..1533445 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PU624_RS10835 (PU624_10835) 1529795..1532014 + 2220 WP_283547619.1 catalase/peroxidase HPI -
PU624_RS10840 (PU624_10840) 1532115..1533137 - 1023 WP_283547620.1 HipA domain-containing protein Toxin
PU624_RS10845 (PU624_10845) 1533134..1533445 - 312 WP_283547621.1 HipA N-terminal domain-containing protein Antitoxin
PU624_RS10850 (PU624_10850) 1533430..1533774 - 345 WP_283547622.1 XRE family transcriptional regulator -
PU624_RS10860 (PU624_10860) 1534549..1535670 + 1122 WP_283547623.1 Gfo/Idh/MocA family oxidoreductase -
PU624_RS10865 (PU624_10865) 1535761..1536591 - 831 WP_283547624.1 glycosyltransferase family 8 protein -
PU624_RS10870 (PU624_10870) 1536604..1537986 - 1383 WP_283547625.1 D-arabinono-1,4-lactone oxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(58-260)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 341 a.a.        Molecular weight: 38402.97 Da        Isoelectric Point: 6.5066

>T272970 WP_283547620.1 NZ_CP118269:c1533137-1532115 [Pantoea sp. Lij88]
MNAERCLITLNRLKESELKTGYSSKGIRHLLGSQDVALTLPFTRSQFIQELPERQKGMSISGYQPKLSLRLEKGELVVVS
NDGTYILKPSPEEYPHLAENEHATMCVMQRLKFDVPPFGLMAFRHDENRPRELAFVIKRYDRSEAENARLHQEQLDGAMG
LGDKYGRIGNNKAISYERAAKFLNTRVSNSLKSKRDLFLRIVYAYVLGNNDFHLRNIGIILPEKNSPFLAPVYDFISVVP
YPAAFGEYLALPLLEGEENDGGNAPGINSEYGEYLGADFILLAQGMDINPALARKWLSGVVSQHQLIIDTYTESHMPELP
REVVLDYVARRITLLAVTEI

Download         Length: 1023 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11794.66 Da        Isoelectric Point: 5.8397

>AT272970 WP_283547621.1 NZ_CP118269:c1533445-1533134 [Pantoea sp. Lij88]
MARKIEVWLYNKLAGTLSEEQSGYTFCYLPAYRGCAISLSMPVRPEPYLSEDLHPFFKGLAPEGWLRKRYSEIQKIDDND
LFGLLMKNGNDMLGAVVFKEITP

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References