Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 233246..233897 Replicon plasmid unnamed1
Accession NZ_CP118267
Organism Pantoea sp. Lij88

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PU624_RS01280 Protein ID WP_283545056.1
Coordinates 233553..233897 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PU624_RS01275 Protein ID WP_283545055.1
Coordinates 233246..233560 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PU624_RS01250 (PU624_01250) 229188..229490 - 303 WP_283545050.1 type 1 fimbrial protein -
PU624_RS01255 (PU624_01255) 229962..230381 - 420 WP_283545051.1 VOC family protein -
PU624_RS01260 (PU624_01260) 230399..231289 - 891 WP_283545052.1 LysR family transcriptional regulator -
PU624_RS01265 (PU624_01265) 231429..232280 + 852 WP_283545053.1 Vmh family MBL fold metallo-hydrolase -
PU624_RS01270 (PU624_01270) 232360..233031 - 672 WP_283545054.1 hypothetical protein -
PU624_RS01275 (PU624_01275) 233246..233560 - 315 WP_283545055.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
PU624_RS01280 (PU624_01280) 233553..233897 - 345 WP_283545056.1 toxin Toxin
PU624_RS01285 (PU624_01285) 233983..234885 - 903 WP_283545057.1 LysR family transcriptional regulator -
PU624_RS01290 (PU624_01290) 234983..236041 + 1059 WP_283545058.1 SDR family oxidoreductase -
PU624_RS01295 (PU624_01295) 236088..236966 - 879 WP_283545059.1 23S rRNA pseudouridine(2604) synthase RluF -
PU624_RS01300 (PU624_01300) 237070..237540 - 471 WP_283545060.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..634148 634148


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(17-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13429.35 Da        Isoelectric Point: 9.7093

>T272968 WP_283545056.1 NZ_CP118267:c233897-233553 [Pantoea sp. Lij88]
MDALFIELSSFQKYRADYLSDDQFRLFQNMLLADPEKGDLIPDTGGLRKVRFRDERRHKGARGGIRVIYYWTNAQCQFIL
FTIYDKNLRDDLTKQQRDALATALNVIKKGLRHD

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12088.86 Da        Isoelectric Point: 9.6240

>AT272968 WP_283545055.1 NZ_CP118267:c233560-233246 [Pantoea sp. Lij88]
MTERDIFSELMTGMQELKDHQEGKITLKSHKVTKRAPVTIAPQELRDVREKLNLSQAVFAHYLHTGETTYQNWEQGRARP
NAQAVLLIRMVQQNPETLKTLEKF

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References