272932

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) yonT-as-bsrE/-
Location 2186877..2187094 Replicon chromosome
Accession NZ_CP118167
Organism Bacillus subtilis strain 21855

Toxin (Protein)


Gene name yonT Uniprot ID A0A6H0WKE8
Locus tag PUW21_RS11235 Protein ID WP_032721653.1
Coordinates 2186877..2187053 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2186994..2187094 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUW21_RS11185 (2182549) 2182549..2182776 - 228 WP_059293799.1 helix-turn-helix transcriptional regulator -
PUW21_RS11190 (2183007) 2183007..2183318 - 312 WP_059293798.1 hypothetical protein -
PUW21_RS11195 (2183446) 2183446..2183772 - 327 WP_059293797.1 hypothetical protein -
PUW21_RS11200 (2183787) 2183787..2184062 - 276 WP_059293796.1 hypothetical protein -
PUW21_RS11205 (2184088) 2184088..2184312 - 225 WP_226465935.1 hypothetical protein -
PUW21_RS11210 (2184305) 2184305..2184436 - 132 WP_268396230.1 hypothetical protein -
PUW21_RS11215 (2184484) 2184484..2184738 - 255 WP_032677190.1 hypothetical protein -
PUW21_RS11220 (2185079) 2185079..2186296 - 1218 WP_160245139.1 hypothetical protein -
PUW21_RS11225 (2186378) 2186378..2186566 - 189 WP_114168610.1 hypothetical protein -
PUW21_RS11230 (2186611) 2186611..2186862 - 252 WP_080010576.1 hypothetical protein -
PUW21_RS11235 (2186877) 2186877..2187053 - 177 WP_032721653.1 hypothetical protein Toxin
- (2186994) 2186994..2187094 + 101 NuclAT_0 - Antitoxin
- (2186994) 2186994..2187094 + 101 NuclAT_0 - Antitoxin
- (2186994) 2186994..2187094 + 101 NuclAT_0 - Antitoxin
- (2186994) 2186994..2187094 + 101 NuclAT_0 - Antitoxin
PUW21_RS11240 (2188079) 2188079..2188273 + 195 WP_004399291.1 hypothetical protein -
PUW21_RS11245 (2188313) 2188313..2190838 + 2526 WP_274357892.1 hypothetical protein -
PUW21_RS11250 (2191091) 2191091..2191366 + 276 WP_032721646.1 HU family DNA-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2120487..2245041 124554
- inside Prophage - - 2120487..2243085 122598


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 59 a.a.        Molecular weight: 6850.39 Da        Isoelectric Point: 12.8833

>T272932 WP_032721653.1 NZ_CP118167:c2187053-2186877 [Bacillus subtilis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Download         Length: 177 bp


Antitoxin


Download         Length: 101 bp

>AT272932 NZ_CP118167:2186994-2187094 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A6H0WKE8


Antitoxin

Download structure file

References