Detailed information of TA system TA272931

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2186840..2187053
• Replicon: chromosome
• Accession: NZ_CP118167
• Organism: Bacillus subtilis strain 21855

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: A0A6H0WKE8
• Locus tag: PUW21_RS11235
• Protein ID: WP_032721653.1
• Coordinates: 2186877..2187053 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2186840..2186936 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PUW21_RS11185	2182549..2182776	-	228	WP_059293799.1	helix-turn-helix transcriptional regulator	-
PUW21_RS11190	2183007..2183318	-	312	WP_059293798.1	hypothetical protein	-
PUW21_RS11195	2183446..2183772	-	327	WP_059293797.1	hypothetical protein	-
PUW21_RS11200	2183787..2184062	-	276	WP_059293796.1	hypothetical protein	-
PUW21_RS11205	2184088..2184312	-	225	WP_226465935.1	hypothetical protein	-
PUW21_RS11210	2184305..2184436	-	132	WP_268396230.1	hypothetical protein	-
PUW21_RS11215	2184484..2184738	-	255	WP_032677190.1	hypothetical protein	-
PUW21_RS11220	2185079..2186296	-	1218	WP_160245139.1	hypothetical protein	-
PUW21_RS11225	2186378..2186566	-	189	WP_114168610.1	hypothetical protein	-
PUW21_RS11230	2186611..2186862	-	252	WP_080010576.1	hypothetical protein	-
-	2186840..2186936	+	97	-	-	Antitoxin
PUW21_RS11235	2186877..2187053	-	177	WP_032721653.1	hypothetical protein	Toxin
-	2186994..2187094	+	101	NuclAT_0	-	-
-	2186994..2187094	+	101	NuclAT_0	-	-
-	2186994..2187094	+	101	NuclAT_0	-	-
-	2186994..2187094	+	101	NuclAT_0	-	-
PUW21_RS11240	2188079..2188273	+	195	WP_004399291.1	hypothetical protein	-
PUW21_RS11245	2188313..2190838	+	2526	WP_274357892.1	hypothetical protein	-
PUW21_RS11250	2191091..2191366	+	276	WP_032721646.1	HU family DNA-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2120487..2245041	124554
	-	inside	Prophage	-	-	2120487..2243085	122598

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6850.39 Da
• Isoelectric Point: 12.8833

>T272931 WP_032721653.1 NZ_CP118167:c2187053-2186877 [Bacillus subtilis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 97 bp

>AT272931 NZ_CP118167:2186840-2186936 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCGTGTTATCTGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAGCCGC
TTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: A0A6H0WKE8

Antitoxin