Detailed information of TA system TA272927

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2049369..2049615
• Replicon: chromosome
• Accession: NZ_CP118167
• Organism: Bacillus subtilis strain 21855

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: PUW21_RS10245
• Protein ID: WP_109789044.1
• Coordinates: 2049369..2049461 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2049442..2049615 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PUW21_RS10230	2044528..2044863	+	336	WP_009967409.1	hypothetical protein	-
PUW21_RS10235	2044910..2048515	-	3606	WP_004399367.1	P-loop NTPase fold protein	-
PUW21_RS10240	2048748..2049080	-	333	WP_026009814.1	hypothetical protein	-
PUW21_RS10245	2049369..2049461	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2049442..2049615	-	174	-	-	Antitoxin
PUW21_RS10250	2049730..2050572	-	843	WP_003231327.1	hypothetical protein	-
PUW21_RS10255	2050772..2051230	-	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
PUW21_RS10260	2051240..2053042	-	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
PUW21_RS10265	2053144..2053701	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2025384..2061233	35849
	-	inside	Prophage	-	-	2035354..2061233	25879

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T272927 WP_109789044.1 NZ_CP118167:2049369-2049461 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT272927 NZ_CP118167:c2049615-2049442 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin