Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 761764..762458 Replicon chromosome
Accession NZ_CP118156
Organism Pseudomonas chlororaphis strain ATCC 15926

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PUP74_RS03440 Protein ID WP_274301666.1
Coordinates 761764..762060 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PUP74_RS03445 Protein ID WP_009041852.1
Coordinates 762057..762458 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PUP74_RS03405 (PUP74_03405) 757385..757930 - 546 WP_062823888.1 hypothetical protein -
PUP74_RS03410 (PUP74_03410) 757927..758181 - 255 WP_007926835.1 acyl carrier protein -
PUP74_RS03415 (PUP74_03415) 758191..758451 - 261 WP_007926834.1 phosphopantetheine-binding protein -
PUP74_RS03420 (PUP74_03420) 758426..759241 - 816 WP_009041848.1 lysophospholipid acyltransferase family protein -
PUP74_RS03425 (PUP74_03425) 759217..759948 - 732 WP_274301667.1 beta-ketoacyl synthase chain length factor -
PUP74_RS03430 (PUP74_03430) 760283..761053 + 771 WP_009041850.1 ParA family protein -
PUP74_RS03435 (PUP74_03435) 761092..761526 - 435 WP_062823885.1 thioredoxin TrxC -
PUP74_RS03440 (PUP74_03440) 761764..762060 + 297 WP_274301666.1 type II toxin-antitoxin system HigB family toxin Toxin
PUP74_RS03445 (PUP74_03445) 762057..762458 + 402 WP_009041852.1 transcriptional regulator Antitoxin
PUP74_RS03450 (PUP74_03450) 762462..763925 - 1464 WP_123412254.1 YdiU family protein -
PUP74_RS03455 (PUP74_03455) 763974..767324 - 3351 WP_123573332.1 mechanosensitive channel MscK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, mRNA interferase HigB

(20-90)

Antitoxin

Antitoxin HigA

(15-133)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11587.38 Da        Isoelectric Point: 10.6515

>T272906 WP_274301666.1 NZ_CP118156:761764-762060 [Pseudomonas chlororaphis]
MHIITAKRIWEAKNRWPQSANALETWYRKAKSLNPADFAAIKAVFPATDKVGAFHVFDIGGNKLRIIAVVRYEVRRLYIR
HVLDHHEYDKGRWKEETR

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14854.92 Da        Isoelectric Point: 4.5430

>AT272906 WP_009041852.1 NZ_CP118156:762057-762458 [Pseudomonas chlororaphis]
MNVLVKQAADHWHFVAPVLRKPKTEADYDALVAALDELLDLMGEDENHPVTSLVDIIGDWIEAYDEEHRPMPIASGVDVL
RSLMREHGLTQSDLPGVGAQSVVSEVLSGKRQLNLRQIRWLAERFGVSAEVFI

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References